Clin Orthop Relat Res. 1990 Aug;(257):204-11.

Eosinophilic granuloma. The management of solitary lesions of bone.

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Section of Orthopaedic Surgery, University of Michigan, Ann Arbor.

Abstract

Solitary eosinophilic granuloma (EG) lesions of bone can represent diagnostic and treatment dilemmas for the orthopedic surgeon. A retrospective review of one institution's experience with isolated EG skeletal lesions over a 30-year period was undertaken. Solitary lesions responded well to most treatment modalities (e.g., curettage, excision, and irradiation) and infrequently resulted in functional impairment. While EG involvement in bone can be a manifestation of a systemic histiocytosis, single-focus skeletal involvement appears to be a benign pathophysiologic process.

PMID:: 2199118; [PubMed - indexed for MEDLINE]

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