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An Bras Dermatol. 2011 Jul-Aug;86(4):759-62.

Granulomas of the penis: a rare complication of intravesical therapy with Bacillus Calmette-Guerin.

[Article in English, Portuguese]

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  • 1Serviço de Dermatologia, Hospital Santo António dos Capuchos, Lisboa, Portugal.


Immunotherapy with Bacillus Calmette-Guérin is widely used for treatment and prophylaxis of superficial urothelial cancer. Complications associated with Bacillus Calmette-Guérin treatment are common. The authors describe a case of granulomatous inflammation of the penis associated with intravesical Bacillus Calmette-Guérin therapy, presenting with multiple erythematous and painless nodules located on the glans. A review of the literature is also performed. Granulomatous balanoposthitis is a rare complication of Bacillus Calmette-Guérin immunotherapy, with heterogeneous clinical presentation, which can make the diagnosis difficult. Its clinical recognition is essential for early start of therapy with antitubercular agents and interruption of Bacillus Calmette-Guérin.

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