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Org Biomol Chem. 2011 Oct 26;9(22):7904-12. doi: 10.1039/c1ob06212c. Epub 2011 Oct 4.

Decarboxylative Claisen rearrangement reactions: synthesis and reactivity of alkylidene-substituted indolines.

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  • 1Department of Chemistry, Imperial College London, South Kensington Campus, London, UK SW7 2AZ. jason.camp@nottingham.ac.uk

Abstract

Microwave-assisted decarboxylative Claisen rearrangement (dCr) reactions of substituted acetate derivatives of 3-(hydroxyalkyl)indoles give de-aromatised products. The reactivity of the resultant compounds was evaluated.

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