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Gastroenterol Hepatol (N Y). 2007 Feb;3(2):112-22.

Small intestinal bacterial overgrowth: a comprehensive review.

Author information

  • 1Dr. Dukowicz is a fellow in the Section of Gastroenterology and Hepatology at the Dartmouth-Hitchcock Medical Center.

Abstract

Small intestinal bacterial overgrowth (SIBO), defined as excessive bacteria in the small intestine, remains a poorly understood disease. Initially thought to occur in only a small number of patients, it is now apparent that this disorder is more prevalent than previously thought. Patients with SIBO vary in presentation, from being only mildly symptomatic to suffering from chronic diarrhea, weight loss, and malabsorption. A number of diagnostic tests are currently available, although the optimal treatment regimen remains elusive. Recently there has been renewed interest in SIBO and its putative association with irritable bowel syndrome. In this comprehensive review, we will discuss the epidemiology, pathogenesis, clinical manifestations, diagnosis, and treatment of SIBO.

KEYWORDS:

Bacterial overgrowth; antibiotics; bloating; diarrhea; motility disorders; small intestinal bacterial overgrowth

PMID:
21960820
[PubMed]
PMCID:
PMC3099351
Free PMC Article
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