Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Int J Gynaecol Obstet. 2011 Dec;115(3):285-8. doi: 10.1016/j.ijgo.2011.06.022. Epub 2011 Sep 28.

Effects of valerian on the severity and systemic manifestations of dysmenorrhea.

Author information

  • 1Department of Midwifery, Zanjan Branch, Islamic Azad University, Zanjan, Iran.

Abstract

OBJECTIVE:

To evaluate the impact of valerian-a herb with sedative effects and antispasmodic effects on smooth muscles-on the severity of dysmenorrhea.

METHODS:

In a double-blind, randomized, placebo-controlled trial, 100 students were randomly assigned to receive valerian (n=49) or placebo (n=51). Valerian (dose 255 mg) was given 3 times daily for 3 days beginning at the onset of menstruation, for 2 consecutive menstrual cycles. At baseline and during the intervention cycles, the pain severity was evaluated with a visual analog scale and the systemic manifestations were assessed using a multidimensional verbal scale.

RESULTS:

The pain severity at baseline did not differ significantly between the groups. After the intervention, the pain severity was significantly reduced in both groups (P<0.001), but the extent of the reduction was larger in the valerian group, with the difference between the 2 groups being statistically significant (P<0.05). The total scores of the systemic manifestations associated with dysmenorrhea decreased after the intervention, but there was no significant difference between the groups, with the exception for syncope (P<0.05).

CONCLUSION:

Valerian seems to be an effective treatment for dysmenorrhea, probably because of its antispasmodic effects.

Copyright © 2011 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

PMID:
21959068
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk