Send to:

Choose Destination
See comment in PubMed Commons below
Sci Transl Med. 2011 Sep 28;3(102):102cm29. doi: 10.1126/scitranslmed.3002939.

Disclosure of clinical trial results when product development is abandoned.

Author information

  • 1Department of Neurology, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA.


Currently, sponsors are not required to report the outcomes of clinical research on drugs or devices that do not lead to an approved product. Consequently, the public cannot benefit from scientific information derived from all failed or abandoned drugs and devices. Provisions in the U.S. Food and Drug Administration Amendments Act of 2007 provide an opportunity for the Department of Health and Human Services to rectify this situation. By reporting the results of clinical trials of abandoned products in a publicly accessible database and in the peer-reviewed journal literature, sponsors would satisfy a core ethical obligation of clinical research and enhance translational science.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk