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Ann N Y Acad Sci. 2011 Sep;1232:316-22. doi: 10.1111/j.1749-6632.2011.06070.x.

Esophageal stem cells and 3D-cell culture models.

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  • 1Division of Gastroenterology, University of Texas Southwestern Medical Center and the VA North Texas Health Care System, Dallas, Texas, USA.


The following on esophageal stem cells and 3D-cell culture models contains commentaries on metaplasia through transdifferentiation and through stem cells; transcription factors that may determine an intestinal-like phenotype; the in vitro, organotypic cell culture models; and the role of stem cells in Barrett's esophagus and its dysplastic progression.

© 2011 New York Academy of Sciences.

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