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Clin Nutr. 2012 Feb;31(1):48-52. doi: 10.1016/j.clnu.2011.09.002. Epub 2011 Sep 25.

Performance comparison of peripherally inserted central venous catheters in gastrointestinal surgery: a randomized controlled trial.

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  • 1Department of Gastroenterological Surgery, Osaka University Graduate school of Medicine, 2-2, E-2, Yamadaoka, Suita, Osaka 565-0871, Japan.



Peripherally inserted central venous catheters (PICC) are long-term vascular access devices inserted through a peripheral vein of the arm and serve as an alternative to traditional central venous catheters. Currently different types of PICCs are available. No data, however, are available in regard to materials and tip designs. We designed a prospective, randomized trial comparing two major PICCs with different material and tip design: a silicone catheter with distal side slits (Groshong Catheter) and a polyurethane catheter with open-end tip (PI Catheter).


Twenty-six patients who underwent PICCs placement between August 2010 and December 2010 were enrolled in the study. The primary endpoint was the completion rate of PICC indication. Secondary endpoints were complications rate.


The completion rate of PICC indication was not different significantly (81.8% and 92.9%, p = 0.5648) and the total complication rate were also not different significantly (9.1% and 14.3%, P = 1.0000) between two catheters. In detail, PI Catheter were associated with a significantly higher incidence of catheter occlusion, and Groshong Catheter were associated with a significantly hemorrhages after removal.


There was no difference in the durability and the complication between Groshong Catheter and PI Catheter. (UMIN Clinical Trial Registry UMIN000005451).

Copyright © 2011 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

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