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J Ment Health. 2011 Oct;20(5):484-91. doi: 10.3109/09638237.2011.586741.

Antipsychotic-induced amenorrhea.

Author information

  • 1Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. mary.seeman@utoronto.ca

Abstract

BACKGROUND:

Many antipsychotic drugs used to treat schizophrenia can cause amenorrhea in a significant proportion of women. The overall impact of this side effect has been little studied.

AIM:

To review the literature on the meaning of menstruation to women.

METHOD:

This is a literature review of the meanings of menstruation to women in general, to women of different cultures, and to women with schizophrenia.

RESULTS:

Many women feel ambivalent with respect to menstruation. Its loss can produce difficulties for women suffering from schizophrenia, such as failure to use contraception, pseudocyesis, denial of pregnancy, erroneous perception of early menopause, or loss of the feeling of femininity.

CONCLUSION:

Attempts should be made to avoid the antipsychotic side effect of amenorrhea.

PMID:
21942684
[PubMed - indexed for MEDLINE]
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