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Clin Dev Immunol. 2012;2012:831434. doi: 10.1155/2012/831434. Epub 2011 Sep 21.

Systemic lupus erythematosus and systemic autoimmune connective tissue disorders behind recurrent diastolic heart failure.

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  • 1Unidad de Alta Resolución Hospitalaría (UARH), Pab. 13, -1, Hospital Marqués de Valdecilla, Avenida Marqués de Valdecilla, 39008 Santander, Spain.


Diastolic heart failure (DHF) remains unexplained in some patients with recurrent admissions after full investigation. A study was directed for screening SLE and systemic autoimmune connective tissue disorders in recurrent unexplained DHF patients admitted at a short-stay and intermediate care unit. It was found that systemic autoimmune conditions explained 11% from all of cases. Therapy also prevented new readmissions. Autoimmunity should be investigated in DHF.

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