Double-blind study of 5-hydroxytryptophan versus p...[J Int Med Res. 1990 May-Jun]

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1: J Int Med Res. 1990 May-Jun;18(3):201-9.Links

Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome.

Caruso I, Sarzi Puttini P, Cazzola M, Azzolini V.

Rheumatology Unit, L. Sacco Hospital, Milan, Italy.

A double-blind, placebo-controlled study of the efficacy and tolerability of 5-hydroxytryptophan (5-HTP) was conducted in 50 patients with primary fibromyalgia syndrome. All the clinical parameters studied were significantly improved by treatment with 5-HTP and only mild and transient side-effects were reported. Further controlled studies are required to define properly the value of 5-HTP in patients with primary fibromyalgia syndrome.

PMID: 2193835 [PubMed - indexed for MEDLINE]

Double-blind study of dothiepin versus placebo in the treatment of primary fibromyalgia syndrome. [J Int Med Res. 1987]
Serotonin precursors in chronic primary headache. A double-blind cross-over study with L-5-hydroxytryptophan vs. placebo. [J Neurosurg Sci. 1985]
Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study. [J Int Med Res. 1992]
Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebo-controlled trial. [Arthritis Rheum. 2005]
[Treatment of essential headache in developmental age with L-5-HTP (cross over double-blind study versus placebo)] [Pediatr Med Chir. 1984]
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Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome.

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