Indian J Pathol Microbiol. 2011 Jul-Sep;54(3):594-6.

Hemophagocytic syndrome associated with Plasmodium falciparum infection.

Vinoth PN, Thomas KA, Selvan SM, Suman DF, Scott JX.

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Department of Pediatrics, Sri Ramachandra Medical College, Chennai, India.

Abstract

Hemophagocytic syndrome (HPS) has been associated with infections, hematological malignancies and autoimmune conditions. Malaria is rarely reported to cause HPS. We report a case of an 11-month-old infant with fever, hepatosplenomegaly, pancytopenia, high serum ferritin, hypertriglyceridemia, and bone marrow hemophagocytosis, consistent with hemophagocytic syndrome. Gametocytes of plasmodium falciparum were identified on bone marrow aspiration. Rapid recovery was observed after treatment with antimalarials.

PMID:: 21934231; [PubMed - indexed for MEDLINE]

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Hemophagocytic syndrome associated with Plasmodium falciparum infection.

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