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Strahlenther Onkol. 2011 Oct;187(10):605-10. doi: 10.1007/s00066-011-1145-x. Epub 2011 Sep 19.

Quality assurance for clinical studies in regional deep hyperthermia.

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  • 1Department of Radiation Oncology, University Hospital of Freiburg, Germany. gregor.bruggmoser@uniklinik-freiburg.de



A guideline is provided for the implementation of regional deep hyperthermia treatments under strict rules of quality assurance. The objective is to guarantee a comparable and comprehensible method in the treatment and scientific analysis of hyperthermia. The guideline describes regional deep hyperthermia (RHT) and MR-controlled partial body hyperthermia (PBH) of children, young and adult patients. According to this guideline, hyperthermia treatment is always applied in combination with chemotherapy and/or radiotherapy.


The guideline is based on practical experience from several hyperthermia centers. The procedure allows applying jointly coordinated standards and quality control in hyperthermia for studies.


The guideline contains recommendations for hyperthermia treatments, including indication, preparation, treatment, and standardized analysis.

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