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Dermatol Clin. 2011 Oct;29(4):663-71. doi: 10.1016/j.det.2011.06.007. Epub 2011 Aug 6.

Diagnosis and treatment of patients with autoimmune bullous disorders in Germany.

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  • 1Department of Dermatology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany. enno.schmidt@uk-sh.de

Abstract

In Germany, more than 2000 new patients per year have been calculated to be diagnosed with autoimmune blistering diseases. In a recent survey, the most frequently applied treatment regimens for bullous pemphigoid were class IV topical corticosteroids and oral prednisolone 0.5 mg or 1.0 mg/kg/d plus dapsone or azathioprine. For pemphigus, two-thirds of the clinics applied oral prednisolone at doses of 1.0 mg or 1.5 mg/kg/d and in more than 80% of departments, azathioprine was chosen as concomitant immunosuppressant. High-dose intravenous immunoglobulin, rituximab, and immunoadsorption are increasingly used for refractory patients. Treatment and diagnostic costs are covered by the health insurances when applied according to published expert recommendations.

Copyright © 2011 Elsevier Inc. All rights reserved.

[PubMed - indexed for MEDLINE]
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