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Genome Biol. 2011 Sep 14;12(9):227. doi: 10.1186/gb-2011-12-9-227.

Computational and statistical approaches to analyzing variants identified by exome sequencing.

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  • 1Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

Abstract

New sequencing technology has enabled the identification of thousands of single nucleotide polymorphisms in the exome, and many computational and statistical approaches to identify disease-association signals have emerged.

PMID:
21920052
[PubMed - indexed for MEDLINE]
PMCID:
PMC3308043
Free PMC Article
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