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J Clin Microbiol. 2011 Nov;49(11):4013-5. doi: 10.1128/JCM.01121-11. Epub 2011 Sep 14.

Laboratory-confirmed case of yaws in a 10-year-old boy from the Republic of the Congo.

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  • 1Laboratory Reference and Research Branch, Division of Sexually Transmitted Disease Prevention, NCHHSTP,, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.


We report a case of yaws in a patient with puritic cutaneous eruption who was initially suspected of infection with monkeypox. The diagnosis was established by real-time PCR and sequencing of specific treponemal DNA sequences. This is the first report describing the use of DNA sequencing to identify Treponema pallidum subsp. pertenue-specific sequences in a patient with active yaws.

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