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Chem Commun (Camb). 2011 Oct 21;47(39):10930-2. doi: 10.1039/c1cc11921d. Epub 2011 Sep 12.

Strand exchange reaction modulated fluorescence "off-on" switching of hybridized DNA duplex stabilized silver nanoclusters.

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  • 1State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, PR China.


The fluorescence (FL)"off-on" switching of designed DNA duplex stabilized silver nanoclusters can be accomplished through the control of DNA strand exchange reaction. The successful sequential control of the FL emission of silver nanoclusters in "off-on" switching cycles confirms that the DNA duplex stabilized silver nanoclusters can work as a new kind of DNA FL switch.

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