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    Results: 15

    1.

    Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice.

    Asada N, Takase M, Nakamura J, Oguchi A, Asada M, Suzuki N, Yamamura K, Nagoshi N, Shibata S, Rao TN, Fehling HJ, Fukatsu A, Minegishi N, Kita T, Kimura T, Okano H, Yamamoto M, Yanagita M.

    J Clin Invest. 2011 Oct;121(10):3981-90. doi: 10.1172/JCI57301. Epub 2011 Sep 12.

    PMID:
    21911936
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    2.

    CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions.

    Jang JE, Hod EA, Spitalnik SL, Frenette PS.

    J Clin Invest. 2011 Apr;121(4):1397-401. doi: 10.1172/JCI45336. Epub 2011 Mar 7.

    PMID:
    21383500
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    3.

    Gene therapy by allele selection in a mouse model of beta-thalassemia.

    Eckardt S, Leu NA, Yanchik A, Hatada S, Kyba M, McLaughlin KJ.

    J Clin Invest. 2011 Feb;121(2):623-7.

    PMID:
    21293060
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    4.

    Spontaneous abrogation of the G₂DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients.

    Ceccaldi R, Briot D, Larghero J, Vasquez N, Dubois d'Enghien C, Chamousset D, Noguera ME, Waisfisz Q, Hermine O, Pondarre C, Leblanc T, Gluckman E, Joenje H, Stoppa-Lyonnet D, Socié G, Soulier J.

    J Clin Invest. 2011 Jan;121(1):184-94. doi: 10.1172/JCI43836. Epub 2010 Dec 22.

    PMID:
    21183791
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    5.

    Cytokinesis failure and attenuation: new findings in Fanconi anemia.

    Mason PJ, Bessler M.

    J Clin Invest. 2011 Jan;121(1):27-30. doi: 10.1172/JCI45619. Epub 2010 Dec 22.

    PMID:
    21183785
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    6.

    Mutation of a barrier insulator in the human ankyrin-1 gene is associated with hereditary spherocytosis.

    Gallagher PG, Steiner LA, Liem RI, Owen AN, Cline AP, Seidel NE, Garrett LJ, Bodine DM.

    J Clin Invest. 2010 Dec;120(12):4453-65. doi: 10.1172/JCI42240. Epub 2010 Nov 22.

    PMID:
    21099109
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    7.

    A tincture of hepcidin cures all: the potential for hepcidin therapeutics.

    Bartnikas TB, Fleming MD.

    J Clin Invest. 2010 Dec;120(12):4187-90. doi: 10.1172/JCI45043. Epub 2010 Nov 22.

    PMID:
    21099105
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    8.

    Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.

    Gardenghi S, Ramos P, Marongiu MF, Melchiori L, Breda L, Guy E, Muirhead K, Rao N, Roy CN, Andrews NC, Nemeth E, Follenzi A, An X, Mohandas N, Ginzburg Y, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S.

    J Clin Invest. 2010 Dec;120(12):4466-77. doi: 10.1172/JCI41717. Epub 2010 Nov 22.

    PMID:
    21099112
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    9.

    Geminin deletion from hematopoietic cells causes anemia and thrombocytosis in mice.

    Shinnick KM, Eklund EA, McGarry TJ.

    J Clin Invest. 2010 Dec;120(12):4303-15.

    PMID:
    21041951
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    10.

    Pharmacologic eigenvalues: beating the rap on bone marrow failure.

    Emerson SG, Garrett RW.

    J Clin Invest. 2010 Nov;120(11):3813-5. doi: 10.1172/JCI45060. Epub 2010 Oct 25.

    PMID:
    20972329
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    11.

    Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells.

    Vinciguerra P, Godinho SA, Parmar K, Pellman D, D'Andrea AD.

    J Clin Invest. 2010 Nov;120(11):3834-42.

    PMID:
    20921626
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    12.

    Sonic hedgehog is a critical mediator of erythropoietin-induced cardiac protection in mice.

    Ueda K, Takano H, Niitsuma Y, Hasegawa H, Uchiyama R, Oka T, Miyazaki M, Nakaya H, Komuro I.

    J Clin Invest. 2010 Jun;120(6):2016-29. doi: 10.1172/JCI39896. Epub 2010 May 17.

    PMID:
    20484812
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    13.

    FAVL elevation in human tumors disrupts Fanconi anemia pathway signaling and promotes genomic instability and tumor growth.

    Zhang J, Zhao D, Park HK, Wang H, Dyer RB, Liu W, Klee GG, McNiven MA, Tindall DJ, Molina JR, Fei P.

    J Clin Invest. 2010 May;120(5):1524-34. doi: 10.1172/JCI40908. Epub 2010 Apr 19.

    PMID:
    20407210
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    14.

    Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts.

    Ye H, Jeong SY, Ghosh MC, Kovtunovych G, Silvestri L, Ortillo D, Uchida N, Tisdale J, Camaschella C, Rouault TA.

    J Clin Invest. 2010 May;120(5):1749-61. doi: 10.1172/JCI40372. Epub 2010 Apr 1.

    PMID:
    20364084
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    15.

    Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease.

    Rosch JW, Boyd AR, Hinojosa E, Pestina T, Hu Y, Persons DA, Orihuela CJ, Tuomanen EI.

    J Clin Invest. 2010 Feb;120(2):627-35. doi: 10.1172/JCI39843. Epub 2010 Jan 19.

    PMID:
    20093777
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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