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    Results: 16

    1.

    TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer.

    Starczynowski DT, Lockwood WW, Deléhouzée S, Chari R, Wegrzyn J, Fuller M, Tsao MS, Lam S, Gazdar AF, Lam WL, Karsan A.

    J Clin Invest. 2011 Oct;121(10):4095-105. doi: 10.1172/JCI58818. Epub 2011 Sep 12.

    PMID:
    21911935
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    2.

    The ability of LCRMP-1 to promote cancer invasion by enhancing filopodia formation is antagonized by CRMP-1.

    Pan SH, Chao YC, Hung PF, Chen HY, Yang SC, Chang YL, Wu CT, Chang CC, Wang WL, Chan WK, Wu YY, Che TF, Wang LK, Lin CY, Lee YC, Kuo ML, Lee CH, Chen JJ, Hong TM, Yang PC.

    J Clin Invest. 2011 Aug;121(8):3189-205. doi: 10.1172/JCI42975. Epub 2011 Jul 11.

    PMID:
    21747164
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    3.

    Myeloid-derived suppressor cells are implicated in regulating permissiveness for tumor metastasis during mouse gestation.

    Mauti LA, Le Bitoux MA, Baumer K, Stehle JC, Golshayan D, Provero P, Stamenkovic I.

    J Clin Invest. 2011 Jul;121(7):2794-807. doi: 10.1172/JCI41936. Epub 2011 Jun 6.

    PMID:
    21646719
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    4.

    A dual role for the immune response in a mouse model of inflammation-associated lung cancer.

    Dougan M, Li D, Neuberg D, Mihm M, Googe P, Wong KK, Dranoff G.

    J Clin Invest. 2011 Jun;121(6):2436-46. doi: 10.1172/JCI44796. Epub 2011 May 2.

    PMID:
    21537082
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    5.

    Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.

    Pacheco-Pinedo EC, Durham AC, Stewart KM, Goss AM, Lu MM, Demayo FJ, Morrisey EE.

    J Clin Invest. 2011 May;121(5):1935-45. doi: 10.1172/JCI44871. Epub 2011 Apr 1.

    PMID:
    21490395
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    6.

    Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma.

    Cascone T, Herynk MH, Xu L, Du Z, Kadara H, Nilsson MB, Oborn CJ, Park YY, Erez B, Jacoby JJ, Lee JS, Lin HY, Ciardiello F, Herbst RS, Langley RR, Heymach JV.

    J Clin Invest. 2011 Apr;121(4):1313-28. doi: 10.1172/JCI42405. Epub 2011 Mar 23.

    PMID:
    21436589
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    7.

    The adaptive stroma joining the antiangiogenic resistance front.

    Casanovas O.

    J Clin Invest. 2011 Apr;121(4):1244-7. doi: 10.1172/JCI46430. Epub 2011 Mar 23.

    PMID:
    21436579
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    8.

    The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice.

    Yang Y, Ahn YH, Gibbons DL, Zang Y, Lin W, Thilaganathan N, Alvarez CA, Moreira DC, Creighton CJ, Gregory PA, Goodall GJ, Kurie JM.

    J Clin Invest. 2011 Apr;121(4):1373-85. doi: 10.1172/JCI42579. Epub 2011 Mar 14.

    PMID:
    21403400
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    9.

    Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-κB signaling.

    Qu Y, Wang J, Ray PS, Guo H, Huang J, Shin-Sim M, Bukoye BA, Liu B, Lee AV, Lin X, Huang P, Martens JW, Giuliano AE, Zhang N, Cheng NH, Cui X.

    J Clin Invest. 2011 Jan;121(1):212-25. doi: 10.1172/JCI43144. Epub 2010 Dec 1.

    PMID:
    21123948
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    10.

    Tumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancer.

    Said N, Smith S, Sanchez-Carbayo M, Theodorescu D.

    J Clin Invest. 2011 Jan;121(1):132-47. doi: 10.1172/JCI42912. Epub 2010 Dec 22.

    PMID:
    21183790
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    11.

    Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.

    Vicent S, Chen R, Sayles LC, Lin C, Walker RG, Gillespie AK, Subramanian A, Hinkle G, Yang X, Saif S, Root DE, Huff V, Hahn WC, Sweet-Cordero EA.

    J Clin Invest. 2010 Nov;120(11):3940-52. doi: 10.1172/JCI44165. Epub 2010 Oct 25.

    PMID:
    20972333
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    12.

    Living or dying by RNA processing: caspase expression in NSCLC.

    Shankarling G, Lynch KW.

    J Clin Invest. 2010 Nov;120(11):3798-801. doi: 10.1172/JCI45037. Epub 2010 Oct 25.

    PMID:
    20972326
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    13.

    hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing.

    Goehe RW, Shultz JC, Murudkar C, Usanovic S, Lamour NF, Massey DH, Zhang L, Camidge DR, Shay JW, Minna JD, Chalfant CE.

    J Clin Invest. 2010 Nov;120(11):3923-39. doi: 10.1172/JCI43552. Epub 2010 Oct 25.

    PMID:
    20972334
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    14.

    Modeling metastasis biology and therapy in real time in the mouse lung.

    Mendoza A, Hong SH, Osborne T, Khan MA, Campbell K, Briggs J, Eleswarapu A, Buquo L, Ren L, Hewitt SM, Dakir el H, Garfield S, Walker R, Merlino G, Green JE, Hunter KW, Wakefield LM, Khanna C.

    J Clin Invest. 2010 Aug;120(8):2979-88. doi: 10.1172/JCI40252. Epub 2010 Jul 19. Erratum in: J Clin Invest. 2010 Oct 1;120(10):3735. Dakir, el-H [corrected to Dakir, El Habib].

    PMID:
    20644255
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    15.

    Gankyrin plays an essential role in Ras-induced tumorigenesis through regulation of the RhoA/ROCK pathway in mammalian cells.

    Man JH, Liang B, Gu YX, Zhou T, Li AL, Li T, Jin BF, Bai B, Zhang HY, Zhang WN, Li WH, Gong WL, Li HY, Zhang XM.

    J Clin Invest. 2010 Aug;120(8):2829-41. doi: 10.1172/JCI42542. Epub 2010 Jul 12.

    PMID:
    20628200
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    16.

    hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing.

    Lee CF, Ou DS, Lee SB, Chang LH, Lin RK, Li YS, Upadhyay AK, Cheng X, Wang YC, Hsu HS, Hsiao M, Wu CW, Juan LJ.

    J Clin Invest. 2010 Aug;120(8):2920-30. doi: 10.1172/JCI42275. Epub 2010 Jul 1.

    PMID:
    20592467
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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