Arch Ophthalmol. 2011 Sep;129(9):1132-8. doi: 10.1001/archophthalmol.2011.225.

Central corneal thickness in children.

Pediatric Eye Disease Investigator Group, Bradfield YS, Melia BM, Repka MX, Kaminski BM, Davitt BV, Johnson DA, Kraker RT, Manny RE, Matta NS, Weise KK, Schloff S.

Collaborators (255)

Schloff S, Daffron ED, Host VE, Wolf RA, Silbert DI, Singman EL, Matta NS, Brubaker CM, Burkhart TL, Garcia SA, Gilmore TD, Jostes DM, Keefer CM, Keene AB, Leckemby GL, Tamkins SM, Perlman AS, Olivares EM, Parra M, Exposito Y, Fernandez SM, Singh DS, Cruz OA, Davitt BV, Anderson JS, Miyazaki EA, Ahmad F, Grant AD, Shultz W, Talley BE, Johnson DA, Drake K, Suh DW, Mendoza MN, Parrino A, Countryman RJ, Craig SL, Fergus LM, Hall AD, Spillman JL, Spooner GA, Taylor DC, Frazier M, Hopkins KT, Marsh-Tootle WL, Walk JM, Weise KK, Baldwin CH, Hill MP, Cotter SA, Barnhardt CN, Chen AM, Chu RH, Edwards LM, Heyman CL, Huang K, Roberts TL, Song E, Wei JX, Bartolacci MM, Parker SM, Ticho BH, Khammar AJ, Clausius DA, Coletta JB, Giers SL, Imler BC, Silva C, Manny RE, Fern KD, Solis GG, Enyedi LB, Freedman SF, Lin AA, Wallace DK, Yanovitch TL, Young TL, Jones SK, Fuller CE, Headen CW, Kashyap NX, Rodriguez IJ, Sala NA, Whitling BH, Hodde RM, Zeto VL, Petersen DB, McMurtrey JR, Morrell BA, Sylvester KL, Davis PL, Anderson KA, Hulett KR, Bloomquist CS, Velazquez SJ, Gearinger MD, Francis D, Aaker JD, Addams LM, Lambert SR, Hutchinson AK, Lenhart PD, Robb RA, Shainberg MJ, Esmail FQ, Phoenix VP, Repka MX, Christoff AX, Goodman CR, Liu X, Astle WF, Cooper LL, Romanchuk KG, Hebert AM, Peddie HJ, Ruddell S, Sandusky HN, Beer TL, Berscheid C, Kerr C, Liu SX, Racine MK, Bremer DL, Cassady CM, Golden RP, Rogers DL, Rogers GL, Fellows RR, Wagner AJ, Forbes BJ, Anninger WV, Binenbaum G, Davidson SL, Mills MD, Quinn GE, Karp KA, Kilmartin S, Summers CG, Anderson JS, Bothun ED, Christiansen SP, Holleschau AM, de Melo AI, Downes SJ, Hogue KM, Merrill KS, Karr DJ, Reznick LG, Stout AU, Summers AI, Wheeler DT, Bonsall DJ, Lopper SL, North RB, Bowman CS, Donahue SP, Kehler LF, Morrison DG, Fraine LA, Franklin CC, Teed RW, Cole KB, Bozic ME, Bradham CU, Glaser SR, Pacheco MM, Senderowitsch N, Girgis NM, Tea YC, Tyler JA, Bade A, Bacal DA, Martin D, Moran KD, O'Hara M, Bartolacci MM, Van Wolferen M, Goldblum TA, Alfaro A, Bradfield YS, France TD, Soderling BH, Longmuir S, Leon A, Olson RJ, Ottar Pfeifer WI, Donahue JP, Silvia ME, Branco DP, Levada AJ, Capobianco C, Walker TL, Abrams MJ, Ingala LJ, Silva G, Neely DE, Whitaker ME, Robbins SL, Castro EF, Roa A, Kraker RT, Beck RW, Cagnina-Morales CM, Cagnina DA, Chandler DL, Clark LE, Costa C, Diamond ER, Donahue Q, Fimbel BP, Foster NC, Gumke MR, Kaminski BM, Lazar EL, Lee SV, Lester LA, Melia BM, Moke PS, Philips M, Rojas DE, Shrader SL, Everett DF, Bradfield YS, Repka MX, Davitt BV, Neely DE, Kraker RT, Melia BM, Bradfield YS, Davitt BV, Freedman SF, Holmes JM, Melia BM, Neely DE, Repka MX, Silbert DI, Suh DW, Tucker DL, Holmes JM, Bacal DA, Beck RW, Birch EE, Christiansen SP, Cotter SA, Everett DF, Hoover DL, Huston PA, Kraker RT, Lee KA, Matta NS, Morrison DG, Repka MX, Rutstein RP, Scheiman MM, Wallace DK.

Source

Jaeb Center for Health Research, Tampa, FL 33647, USA. pedig@jaeb.org

Abstract

OBJECTIVES:

To determine the central corneal thickness (CCT) in healthy white, African American, and Hispanic children from birth to 17 years of age and to determine whether CCT varies by age, race, or ethnicity.

DESIGN:

Prospective observational multicenter study. Central corneal thickness was measured with a handheld contact pachymeter.

RESULTS:

A total of 2079 children were included in the study, with ages ranging from birth to 17 years. Included were 807 whites, 494 Hispanics, and 474 African Americans, in addition to Asian, unknown race, and mixed-race individuals. African American children had thinner corneas on average than that of both white and Hispanic children (P < .001 for both) by approximately 20 μm. Thicker median CCT was observed with each successive year of age from age 1 to 11 years, with year-to-year differences steadily decreasing and reaching a plateau after age 11 at 573 μm in white and Hispanic children and 551 μm in African American children. For every 100 μm of thicker CCT measured, the intraocular pressure was 1.5 mm Hg higher on average (P < .001). For every diopter of increased myopic refractive error, CCT was 1 μm thinner on average (P < .001).

CONCLUSIONS:

Median CCT increases with age from 1 to 11 years, with the greatest increase present in the youngest age groups. African American children on average have thinner central corneas than white and Hispanic children, whereas white and Hispanic children demonstrate similar CCT.