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Nat Neurosci. 2011 Sep 11;14(10):1330-7. doi: 10.1038/nn.2901.

Grid cells generate an analog error-correcting code for singularly precise neural computation.

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  • 1Center for Learning and Memory, University of Texas at Austin, Austin, Texas, USA.

Abstract

Entorhinal grid cells in mammals fire as a function of animal location, with spatially periodic response patterns. This nonlocal periodic representation of location, a local variable, is unlike other neural codes. There is no theoretical explanation for why such a code should exist. We examined how accurately the grid code with noisy neurons allows an ideal observer to estimate location and found this code to be a previously unknown type of population code with unprecedented robustness to noise. In particular, the representational accuracy attained by grid cells over the coding range was in a qualitatively different class from what is possible with observed sensory and motor population codes. We found that a simple neural network can effectively correct the grid code. To the best of our knowledge, these results are the first demonstration that the brain contains, and may exploit, powerful error-correcting codes for analog variables.

© 2011 Nature America, Inc. All rights reserved.

PMID:
21909090
[PubMed - indexed for MEDLINE]
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