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Silencing of the SNARE protein NAPA sensitizes cancer cells to cisplatin by inducing ERK1/2 signaling, synoviolin ubiquitination and p53 accumulation.
Wu ZZ, Sun NK, Chien KY, Chao CC.
Biochem Pharmacol. 2011 Dec 1;82(11):1630-40. Epub 2011 Aug 31.
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ER stress differentially regulates the stabilities of ERAD ubiquitin ligases and their substrates.
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