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Am J Nephrol. 1990;10(1):73-6.

Recurrent allograft antiglomerular basement membrane glomerulonephritis in a patient with Alport's syndrome.

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  • 1Department of Nephrology, Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia.


A patient with Alport's syndrome and chronic renal failure received a cadaver kidney graft. Four months after the transplantation, he developed glomerulonephritis induced by anti-glomerular basement membrane (GBM) antibody. The graft failed, and the patient returned to haemodialysis. Twenty-two months later the patient received a second cadaver kidney graft. Ten months after the second transplant, he developed a recurrent anti-GBM glomerulonephritis. This observation suggests that anti-GBM disease can recur in a second transplanted kidney in a patient with Alport's syndrome.

[PubMed - indexed for MEDLINE]
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