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Rheumatol Int. 2012 Oct;32(10):3315-7. Epub 2011 Sep 1.

Drug-induced lupus in anti-TNF-alpha therapy and its treatment with rituximab.

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  • 1Department of Internal Medicine, CES University, Fundación Valle del Lili, Cali, Colombia.

Abstract

We report three patients with rheumatoid arthritis (RA) who were treated with anti-TNF-α agents and who developed drug-induced lupus (DIL). Two of them received etanercept and the remainder adalimumab. We also present the favorable response observed with the withdrawal of the anti-TNF-alpha agents and the introduction of rituximab. Through this intervention, we observed a very good control of the activity of both DIL and RA without additional adverse reactions.

PMID:
21881980
[PubMed - indexed for MEDLINE]
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