Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Trends Microbiol. 2011 Nov;19(11):564-71. doi: 10.1016/j.tim.2011.07.010. Epub 2011 Aug 29.

Cryptococcus gattii: a resurgent fungal pathogen.

Author information

  • 1Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208, USA. vishnu@wadsworth.org

Abstract

Cryptococcus gattii and Cryptococcus neoformans are causal agents of cryptococcosis, which manifests as pneumonia and meningitis. C. gattii has recently received widespread attention owing to outbreaks in British Columbia, Canada and the US Pacific Northwest. The biology of this tree-dwelling yeast is relatively unexplored, and there are few clues about how it causes infections in humans and animals. In this review, we summarize recent discoveries about C. gattii genetics and its ecological niche and highlight areas ripe for future exploration. Increased focus on epidemiology, ecological modeling and host-pathogen interactions is expected to yield a better understanding of this enigmatic yeast, and ultimately lead to better measures for its control.

Copyright © 2011 Elsevier Ltd. All rights reserved.

PMID:
21880492
[PubMed - indexed for MEDLINE]
PMCID:
PMC3205261
Free PMC Article

Images from this publication.See all images (3)Free text

Figure 1
Figure 2
Figure 3
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk