Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Epidemiology. 2011 Nov;22(6):793-6. doi: 10.1097/EDE.0b013e3182302e8e.

Transmissibility of seasonal and pandemic influenza in a cohort of households in Hong Kong in 2009.

Author information

  • 1School of Public Health, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.

Abstract

BACKGROUND:

The household secondary attack proportion (SAP) is commonly used to measure the transmissibility of an infectious disease.

METHODS:

We analyzed the final outbreak size distributions of pandemic A(H1N1), seasonal A(H1N1), and A(H3N2) infections identified in paired sera collected from members of 117 Hong Kong households in April and in August-October 2009.

RESULTS:

The estimated community probability of infection overall was higher for children than adults; the probability was similar for pandemic A(H1N1) and seasonal A(H3N2) influenza. The household SAP for pandemic A(H1N1) was higher in children than in adults, whereas for seasonal A(H3N2), it was similar in children and adults. The estimated SAPs were similar for seasonal A(H3N2) and pandemic A(H1N1) after excluding persons with higher baseline antibody titers from analysis.

CONCLUSIONS:

Pandemic and seasonal influenza A viruses had similar age-specific transmissibility in a cohort of initially uninfected households, after adjustment for baseline immunity.

Comment in

  • Transmissibility of influenza. [Epidemiology. 2012]
PMID:
21878814
[PubMed - indexed for MEDLINE]
PMCID:
PMC3206962
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Lippincott Williams & Wilkins Icon for PubMed Central
    Loading ...
    Write to the Help Desk