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J Chin Med Assoc. 2011 Aug;74(8):376-9. doi: 10.1016/j.jcma.2011.06.006. Epub 2011 Aug 6.

Primary malignant melanoma of the vagina with repeated local recurrences and brain metastasis.

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  • 1Department of Obstetrics and Gynecology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.

Abstract

Malignant melanoma of the vagina, a very rare malignancy, has a notoriously aggressive behavior associated with a high risk of local recurrence and distant metastasis. At present, there are various treatment options for this disease but no standard guideline. We describe a case of a 54-year-old woman with a locally advanced melanoma of the vagina, who underwent radical surgery, biochemotherapy with interferon-α-2b, chemotherapy, radiotherapy, and repeat excision of local recurrent lesions and brain metastasis. In conclusion, malignant melanoma of the vagina has a high risk for local recurrence. Repeated local excision followed by biochemotherapy is a tolerable treatment.

Copyright © 2011. Published by Elsevier B.V.

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