Cell-based therapies for tendon and ligament injuries

A G L Alves; Allison A Stewart; J Dudhia; Y Kasashima; A E Goodship; R K W Smith

doi:10.1016/j.cveq.2011.06.001

Cell-based therapies for tendon and ligament injuries

Vet Clin North Am Equine Pract. 2011 Aug;27(2):315-33. doi: 10.1016/j.cveq.2011.06.001.

Authors

A G L Alves¹, Allison A Stewart, J Dudhia, Y Kasashima, A E Goodship, R K W Smith

Affiliation

¹ Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, São Paulo State University, Botucatu, São Paulo 18618970, Brazil.

PMID: 21872761
DOI: 10.1016/j.cveq.2011.06.001

Abstract

Tendon and ligament injuries have proved difficult to treat effectively. Cell-based therapies offer the potential to harness the complex protein synthetic machinery of the cell to induce a regenerative response rather than fibrous scarring. This article reviews the current state of play with respect to the clinically used cell preparations for the treatment of tendon and ligaments overstrain injuries.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Transplantation / methods
Cell Transplantation / veterinary*
Horse Diseases / therapy*
Horses
Ligaments / injuries*
Tendon Injuries / therapy
Tendon Injuries / veterinary*