Display Settings:

Format

Send to:

Choose Destination
Clin Neurol Neurosurg. 2011 Nov;113(9):703-10. doi: 10.1016/j.clineuro.2011.07.024. Epub 2011 Aug 26.

The central nervous system solitary fibrous tumor: a review of clinical, imaging and pathologic findings among all reported cases from 1996 to 2010.

Author information

  • 1Department of Neurosurgery, University of Florida College of Medicine, Gainesville, FL, USA. kyle.fargen@neurosurgery.ufl.edu

Abstract

OBJECTIVE:

Central nervous system (CNS) solitary fibrous tumor (SFT) is a rare lesion first identified as a unique entity in 1996. We describe two cases treated at the University of Florida followed by a review of all reported cases of CNS SFT between 1996 and 2010.

METHODS:

A review of the literature was performed to identify all reported cases of CNS SFT.

RESULTS:

189 cases (including the two presented herein) were discovered, of which 46 were spinal and 143 were intracranial. Demographic, imaging, and pathologic findings are presented. Roughly 6% of reported lesions are malignant. Subtotal resection (STR) was associated with a 16-fold increased odds of recurrence (OR 15.9, 95% CI 5.5-46.1), although mean follow-up was shorter in those cases of GTR without recurrence.

CONCLUSION:

CNS SFT is a rare lesion. Six percent of lesions are malignant. GTR is superior to STR although the degree of superiority is not clear.

Copyright © 2011 Elsevier B.V. All rights reserved.

PMID:
21872387
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk