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J Nucl Med Technol. 2011 Dec;39(4):249-51. doi: 10.2967/jnmt.111.089011. Epub 2011 Aug 24.

Inadvertent intraarterial injection of ¹⁸F-FDG: a case report and literature review of hot forearm and hot hand signs.

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  • 1Department of Nuclear Medicine, Peking Union Medical College Hospital, Beijing, China.


Unintentional intraarterial injection of radiotracers may cause artifacts leading to difficulties in accurately interpreting PET/CT images. We report a case of a 73-y-old man with a history of metastatic colon cancer who underwent a PET/CT scan for restaging. In the PET scan, there was intense and diffuse distribution of (18)F-FDG in his left forearm and hand. This is a classic sign of an accidental intraarterial injection of (18)F-FDG in the antecubital region. Similar phenomena after inadvertent intraarterial injection of other radiotracers are reviewed. The associated risk factors, preventive measures, and radiation dose to the arm are discussed.

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