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Clin Infect Dis. 2011 Sep;53(6):572-4. doi: 10.1093/cid/cir483.

Failure of the Milwaukee protocol in a child with rabies.

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  • 1Division of Critical Care Medicine, Children's Hospital & Research Center Oakland, California 94609, USA.


Rabies has the highest case-fatality rate of all infectious diseases, with 50,000 cases occurring annually worldwide. In 2004 an unvaccinated adolescent survived after novel therapy. We report the management of a child with rabies. Although the implementation of this same therapeutic protocol was successful, the child died after 1 month of hospitalization.

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