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J Occup Environ Med. 2011 Sep;53(9):966-74. doi: 10.1097/JOM.0b013e31822a3596.

Sarcoidosis diagnosed after September 11, 2001, among adults exposed to the World Trade Center disaster.

Author information

  • 1World Trade Center Health Registry, New York City Department of Healthand Mental Hygiene, 42-09 28th St, 7th floor, Long Island City, NY 11101, USA. hjordan1@health.nyc.gov

Abstract

OBJECTIVE:

Explore relationships between World Trade Center (WTC) exposures and sarcoidosis.

METHODS:

Sarcoidosis has been reported after exposure to the WTC disaster. We ascertained biopsy-proven post-9/11 sarcoidosis among WTC Health Registry enrollees. Cases diagnosed after Registry enrollment were included in a nested case-control study. Controls were matched to cases on age, sex, race or ethnicity, and eligibility group (eg, rescue or recovery worker).

RESULTS:

We identified 43 cases of post-9/11 sarcoidosis. Twenty-eight incident cases and 109 controls were included in the case-control analysis. Working on the WTC debris pile was associated with sarcoidosis (odds ratio 9.1, 95% confidence interval 1.1 to 74.0), but WTC dust cloud exposure was not (odds ratio 1.0, 95% confidence interval 0.4 to 2.8).

CONCLUSIONS:

Working on the WTC debris pile was associated with an elevated risk of post-9/11 sarcoidosis. Occupationally exposed workers may be at increased risk.

(C)2011The American College of Occupational and Environmental Medicine

Comment in

PMID:
21860326
[PubMed - indexed for MEDLINE]
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