Four-year evaluation of the effect of vaccination against Coxiella burnetii on reduction of animal infection and environmental contamination in a naturally infected dairy sheep flock

Appl Environ Microbiol. 2011 Oct;77(20):7405-7. doi: 10.1128/AEM.05530-11. Epub 2011 Aug 19.

Abstract

Vaccination is considered one of the best options for controlling Coxiella burnetii infection in livestock. The efficacy of a phase I vaccine was investigated over 4 years in a sheep flock with confirmed C. burnetii infection. Shedding was not detected in ewes and yearlings in the last 2 years, but C. burnetii still persisted in the environment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacterial Shedding / immunology
  • Bacterial Vaccines / administration & dosage*
  • Bacterial Vaccines / immunology*
  • Coxiella burnetii / immunology
  • Coxiella burnetii / isolation & purification*
  • Environmental Microbiology
  • Follow-Up Studies
  • Q Fever / epidemiology
  • Q Fever / microbiology
  • Q Fever / prevention & control
  • Q Fever / veterinary*
  • Sheep
  • Sheep Diseases / epidemiology*
  • Sheep Diseases / microbiology
  • Sheep Diseases / prevention & control*
  • Treatment Outcome
  • Vaccination / methods
  • Vaccines, Inactivated / administration & dosage
  • Vaccines, Inactivated / immunology

Substances

  • Bacterial Vaccines
  • Vaccines, Inactivated