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J Cataract Refract Surg. 2011 Oct;37(10):1858-64. doi: 10.1016/j.jcrs.2011.05.023.

Visual outcome and contrast sensitivity after photorefractive keratectomy in low to moderate myopia: wavefront-optimized versus conventional methods.

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  • 1Department of Ophthalmology, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.



To compare visual outcomes and contrast sensitivity after wavefront-optimized or conventional photorefractive keratectomy (PRK) in myopic patients with or without astigmatism.


Vanak Eye Surgery Center, Tehran, Iran.


Comparative case series.


Patients with low to moderate myopia with or without astigmatism were allocated into 2 groups. The study group was treated with wavefront-optimized PRK (Allegretto Wave Eye-Q software version 2.020 default treatment) and the control group, with conventional PRK (Technolas 217z). In all cases, treatments were bilateral and performed with the same device. Baseline and 3-month postoperative measures were uncorrected and corrected distance visual acuities, manifest refraction, and contrast sensitivity.


Each group comprised 66 eyes. The mean preoperative spherical equivalent refraction improved from -2.99 diopters (D) ± 1.02 (SD) preoperatively to -0.08 ± 0.26 D 3 months postoperatively in the study group and from -2.66 ± 0.95 D to 0.01 ± 0.30 D, respectively, in the control group. In both groups, the postoperative mesopic and photopic contrast sensitivity decreased significantly at most spatial frequencies. The postoperative decrease in contrast sensitivity in both groups was comparable except at spatial frequencies of 3 cycles per degree (cpd) under mesopic conditions and 12 cpd under photopic conditions, frequencies at which the control group had a greater reduction.


Visual acuity and refractive error outcomes were similar in both treatment groups. After 3 months, mesopic and photopic contrast sensitivity were significantly decreased in both groups; the reduction in the 2 groups was almost comparable.


No author has a financial or proprietary interest in any material or method mentioned.

Copyright © 2011 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

[PubMed - indexed for MEDLINE]
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