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Arch Dermatol Res. 2011 Nov;303(9):623-4. doi: 10.1007/s00403-011-1165-5.

Why vitiligo is associated with fewer risk of skin cancer?: providing a molecular mechanism.

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  • 1Department of Dermatology, Jundishapur University of Medical Sciences, Ahvaz, Iran.


Vitiligo is an acquired clinical conundrum, characterized by white areas on the skin due to loss of functional melanocytes. Various studies demonstrated that vitiligo is associated with fewer risk of skin cancer but no exact molecular explanation for this interesting observation has been described. This article reviews the exist documents and provides a molecular mechanism for this negative association.

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