Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Case Rep Gastroenterol. 2011 May;5(2):416-21. doi: 10.1159/000330480. Epub 2011 Jul 22.

Metastatic Kaposi's Sarcoma with Perirectal Involvement Diagnosed with Endoscopic Ultrasound-Guided EchoBrush Cytology Sampling.

Author information

  • 1Division of Gastroenterology and Hepatology, University of Wisconsin Hospital and Clinics, Madison, Wisc., USA.

Abstract

AIDS-related Kaposi's sarcoma (KS) is a low-grade vascular tumor that occurs in association with human herpesvirus 8 infection. Here we report the case of a 21-year-old male with recently diagnosed cutaneous KS who presented with rectal bleeding and anal pruritus. Initial endoscopic evaluation was nondiagnostic. CT imaging showed diffuse lymphadenopathy including perirectal involvement which was suspicious for metastatic KS. Echoendoscopy with needle biopsies and EchoBrush sampling of the lymph nodes revealed spindle cells confirming metastatic KS. Treatment was initiated with liposomal doxorubicin resulting in rapid improvement of the skin lesions. After treatment completion, repeat CT imaging showed improved lymphadenopathy. No further rectal bleeding or perianal pruritus was reported. Although the EchoBrush has previously been used to aid in the diagnosis of pancreatic lesions, this report describes a novel use of EchoBrush to diagnose KS from perirectal lymph nodes.

KEYWORDS:

Acquired immunodeficiency; EchoBrush; Endoscopic ultrasound; Human herpesvirus 8; Human immunodeficiency virus; Kaposi's sarcoma; Metastasis

PMID:
21829398
[PubMed]
PMCID:
PMC3151002
Free PMC Article

Images from this publication.See all images (4)Free text

Fig. 1
Fig. 2
Fig. 3
Fig. 4
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for S. Karger AG, Basel, Switzerland Icon for PubMed Central
    Loading ...
    Write to the Help Desk