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Chem Commun (Camb). 2011 Sep 21;47(35):9801-3. doi: 10.1039/c1cc14076k. Epub 2011 Aug 5.

High-throughput age synchronisation of Caenorhabditis elegans.

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  • 1Department of Chemistry, Imperial College London, London, UK.


We present a passive microfluidic strategy for sorting adult C. elegans nematodes on the basis of age and size. The separation mechanism takes advantage of phenotypic differences between 'adult' and 'juvenile' organisms and their behaviour in microfluidic architectures. In brief, the microfluidic device allows worms to sort themselves in a passive manner.

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