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    PLoS One. 2011;6(7):e22326. Epub 2011 Jul 27.

    Identification of reproduction-specific genes associated with maturation and estrogen exposure in a marine bivalve Mytilus edulis.

    Source

    Department of Biology and Environmental Science, University of Sussex, Brighton, United Kingdom.

    Abstract

    BACKGROUND:

    While it is established that vertebrate-like steroids, particularly estrogens (estradiol, estrone) and androgens (testosterone), are present in various tissues of molluscs, it is still unclear what role these play in reproductive endocrinology in such organisms. This is despite the significant commercial shellfishery interest in several bivalve species and their decline.

    METHODOLOGY/PRINCIPAL FINDINGS:

    Using suppression subtraction hybridisation of mussel gonad samples at two stages (early and mature) of gametogenesis and (in parallel) following controlled laboratory estrogen exposure, we isolate several differentially regulated genes including testis-specific kinases, vitelline lysin and envelope sequences.

    CONCLUSIONS:

    The differentially expressed mRNAs isolated provide evidence that mussels may be impacted by exogenous estrogen exposure.

    PMID:
    21818309
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC3144882
    Free PMC Article

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