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J Cardiovasc Dis Res. 2011 Apr;2(2):96-103. doi: 10.4103/0975-3583.83035.

Inflammation and diabetic retinal microvascular complications.

Author information

  • 1Vascular Biology Center, Georgia Health Sciences University, Augusta, Georgia, USA.

Abstract

Diabetic retinopathy (DR) is one of the most common complications of diabetes and is a leading cause of blindness in people of the working age in Western countries. A major pathology of DR is microvascular complications such as non-perfused vessels, microaneurysms, dot/blot hemorrhages, cotton-wool spots, venous beading, vascular loops, vascular leakage and neovascularization. Multiple mechanisms are involved in these alternations. This review will focus on the role of inflammation in diabetic retinal microvascular complications and discuss the potential therapies by targeting inflammation.

KEYWORDS:

Diabetic retinopathy; inflammation; microvascular complications

PMID:
21814413
[PubMed]
PMCID:
PMC3144626
Free PMC Article

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