Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Int J Biomed Imaging. 2011;2011:370701. doi: 10.1155/2011/370701. Epub 2011 Jul 25.

Molecular imaging in tumor angiogenesis and relevant drug research.

Author information

  • 1Intelligent Medical Research Center, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.

Abstract

Molecular imaging, including fluorescence imaging (FMI), bioluminescence imaging (BLI), positron emission tomography (PET), single-photon emission-computed tomography (SPECT), and computed tomography (CT), has a pivotal role in the process of tumor and relevant drug research. CT, especially Micro-CT, can provide the anatomic information for a region of interest (ROI); PET and SPECT can provide functional information for the ROI. BLI and FMI can provide optical information for an ROI. Tumor angiogenesis and relevant drug development is a lengthy, high-risk, and costly process, in which a novel drug needs about 10-15 years of testing to obtain Federal Drug Association (FDA) approval. Molecular imaging can enhance the development process by understanding the tumor mechanisms and drug activity. In this paper, we focus on tumor angiogenesis, and we review the characteristics of molecular imaging modalities and their applications in tumor angiogenesis and relevant drug research.

PMID:
21808639
[PubMed]
PMCID:
PMC3144661
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Hindawi Publishing Corporation Icon for PubMed Central
    Loading ...
    Write to the Help Desk