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Ageing Res Rev. 2012 Jan;11(1):150-62. doi: 10.1016/j.arr.2011.07.001. Epub 2011 Jul 19.

The grey mouse lemur: a non-human primate model for ageing studies.

Author information

  • 1CNRS UMR 7179, MNHN, Brunoy, France.

Abstract

The use of non-human primate models is required to understand the ageing process and evaluate new therapies against age-associated pathologies. The present article summarizes all the contributions of the grey mouse lemur Microcebus murinus, a small nocturnal prosimian primate, to the understanding of the mechanisms of ageing. Results from studies of both healthy and pathological ageing research on the grey mouse lemur demonstrated that this animal is a unique model to study age-dependent changes in endocrine systems, biological rhythms, thermoregulation, sensorial, cerebral and cognitive functions.

Copyright © 2011 Elsevier B.V. All rights reserved.

PMID:
21802530
[PubMed - indexed for MEDLINE]
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