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Indian J Sex Transm Dis. 2011 Jan;32(1):9-13. doi: 10.4103/0253-7184.81247.

An overview of post exposure prophylaxis for HIV in health care personals: Gujarat scenario.

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  • 1Associate Consultant, Infectious Disease & Tropical Medicine Clinic, and Ex. Regional Co-ordinator - CST (NACO), Ahmedabad.


Average risk of acquiring HIV infection after a percutaneous exposure to HIV infected blood is 0.3%. Post exposure prophylaxis (PEP) for HIV refers to a set of comprehensive services to prevent HIV infection in exposed individuals where the exposure can be occupational/ non occupational and a provision of short term (28 days) antiretroviral drugs are given depending on the risk assessment. It also includes counselling and relevant laboratory investigations after taking informed consent of the exposed person and source. PEP inhibits the replication of the initial inoculum of virus and thereby prevents establishment of chronic HIV infection, and is best effective when initiated within 2 hours but certainly within 72 hours. Present communication deals with the registry of 278 cases of PEP from Gujarat in terms of various determinants, their status and the outcome in terms of HIV sero positivity.


Antiretroviral drugs; HIV; health care personals; post exposure prophylaxis

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