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Chem Soc Rev. 2012 Feb 7;41(3):1130-72. doi: 10.1039/c1cs15132k. Epub 2011 Jul 28.

Fluorescent indicators based on BODIPY.

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  • 1Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200f - bus 02404, 3001 Heverlee (Leuven), Belgium.

Erratum in

  • Chem Soc Rev. 2012 Dec 21;41(24):8212.


This critical review covers the advances made using the 4-bora-3a,4a-diaza-s-indacene (BODIPY) scaffold as a fluorophore in the design, synthesis and application of fluorescent indicators for pH, metal ions, anions, biomolecules, reactive oxygen species, reactive nitrogen species, redox potential, chemical reactions and various physical phenomena. The sections of the review describing the criteria for rational design of fluorescent indicators and the mathematical expressions for analyzing spectrophotometric and fluorometric titrations are applicable to all fluorescent probes (206 references).

This journal is © The Royal Society of Chemistry 2012

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