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    Eur J Vasc Endovasc Surg. 2011 Oct;42(4):510-6. Epub 2011 Jul 26.

    The impact of gender on prognosis after non-cardiac vascular surgery.

    Source

    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.

    Abstract

    OBJECTIVES:

    The objective was to evaluate the impact of gender on long-term survival of patients who underwent non-cardiac vascular surgery. DESIGN, MATERIAL AND METHODS: Our prospectively collected data contained information on 560 patients undergoing carotid endarterectomy (CEA), 923 elective abdominal aortic aneurysm repairs (AAA) and 1046 lower limb reconstructions (LLR). Patient characteristics and long-term mortality of women were compared to that of men. Kaplan-Meier (KM) survival curves were constructed for men and women, on which we superimposed age- and sex-matched KM survival curves of the general population. Cox proportional hazards regression was used to identify risk factors for mortality.

    RESULTS:

    Men in the CEA group had statistically significant higher all-cause mortality, hazard rate ratio (HRR) 1.41 (95% CI 1.01-1.98) No differences in mortality between the genders were observed in the AAA and LLR groups. Overall, men had more co-morbidities but received more disease-specific medication compared to women. Women retained their higher life expectancy after CEA but lost it in the AAA and LLR groups.

    CONCLUSION:

    Women retain their higher life expectancy after CEA; however, after AAA repair and LLR, this advantage is lost. Both men and women received too little disease-specific medication, but women were worse off.

    Copyright © 2011 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

    PMID:
    21795080
    [PubMed - indexed for MEDLINE]

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