A 10-month-old Yorkshire Terrier was referred for evaluation of an intermittent right thoracic limb lameness that acutely progressed to non-weight-bearing. A diagnosis of bilateral bone cysts of the humeral condyles with a pathologic fracture of the lateral aspect of the right humeral condyle was given following radiographic and histopathologic examination. Bilateral pathology necessitated consideration of treatment modalities other than amputation of the limb, as previously reported. Arthrodesis of the right elbow using a 2.0 mm locking bone plate was performed. The dog did not experience any complications associated with the procedure or the contralateral bone cyst.