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J Cell Biol. 2011 Jul 25;194(2):165-75. doi: 10.1083/jcb.201011152.

Evolution: Tracing the origins of centrioles, cilia, and flagella.

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  • 1Instituto Gulbenkian de Ciência, 6 P-2780-156 Oeiras, Portugal.

Erratum in

  • J Cell Biol. 2011 Oct 17;195(2):341.

Abstract

Centrioles/basal bodies (CBBs) are microtubule-based cylindrical organelles that nucleate the formation of centrosomes, cilia, and flagella. CBBs, cilia, and flagella are ancestral structures; they are present in all major eukaryotic groups. Despite the conservation of their core structure, there is variability in their architecture, function, and biogenesis. Recent genomic and functional studies have provided insight into the evolution of the structure and function of these organelles.

PMID:
21788366
[PubMed - indexed for MEDLINE]
PMCID:
PMC3144413
Free PMC Article
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