Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Surg Clin North Am. 2011 Aug;91(4):755-70, vii. doi: 10.1016/j.suc.2011.04.007. Epub 2011 Jun 8.

Nutrition and gut immunity.

Author information

  • 1Department of Surgery, Surgical Center, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 1138655, Japan.

Abstract

The human intestine contains huge amounts of nonpathologic bacteria surviving in an environment that is beneficial to both the host and the bacterial populations. When short pauses in oral intake occur with minimal alterations in the mucosa-microbial interface, critical illness, with its attendant acidosis, prolonged gastrointestinal tract starvation, exogenous antibiotics, and breakdown in mucosal defenses, renders the host vulnerable to bacterial challenge and also threatens the survival of the bacteria. This review examines the altered innate and adaptive immunologic host defenses that occur as a result of altered oral or enteral intake and/or injury.

Copyright © 2011 Elsevier Inc. All rights reserved.

PMID:
21787966
[PubMed - indexed for MEDLINE]
PMCID:
PMC3144400
Free PMC Article

Images from this publication.See all images (4)Free text

Figure 1
Figure 2
Figure 3
Figure 4
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk