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AIDS Res Ther. 2011 Jul 25;8(1):25. doi: 10.1186/1742-6405-8-25.

Characteristics of HIV-infected women and factors associated with HCV seropositivity in the Republic of Georgia.

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  • 1Infectious Diseases, AIDS and Clinical Immunology Research Center, 16 Al, Kazbegi Avenue, Tbilisi 0160, Georgia. nikoloch@yahoo.com.

Abstract

BACKGROUND:

The aim of this study was to describe the extent of the HIV epidemic among women in the Republic of Georgia and to identify factors associated with HCV co-infection in this population.

FINDINGS:

All women aged ≥18 years who were diagnosed with HIV between 1989 and 2006 were identified through the National HIV/AIDS surveillance database. Medical records were reviewed for demographic characteristics, risk factors and HCV serostatus. A total of 249 women were identified. Only 4% declared injection drug use (IDU); sex work was reported by 9%. Substantial risk factors were identified among the women's sexual partners, nearly 69% of whom were IDUs, 84% were HIV positive and 66% HCV positive. Seventeen percent of women were seropositive for HCV. Factors significantly associated with HCV seropositivity in bivariate analyses among non-IDU women were partner IDU+ [Prevalence ratio (PR): 4.5 (95% CI: 1.4, 14.2)], and partner HCV+ [PR: 7.2 (95% CI: 1.8, 29.5)].

CONCLUSIONS:

The HIV epidemic in the Republic of Georgia is closely tied to the IDU community. Evidence-based interventions targeting IDU and partners of IDU are urgently required to halt the spread of the HIV epidemic in the country.

PMID:
21787384
[PubMed]
PMCID:
PMC3154141
Free PMC Article
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