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Genome Biol. 2011 Jul 25;12(7):121. doi: 10.1186/gb-2011-12-7-121.

Sex lethal and upstream ORFs: a bait-and-trap system for ribosomes.

Author information

  • 1Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

Abstract

An upstream ORF cooperates with Sex lethal to inhibit msl-2 translation during Drosophila sex determination, a biological principle with potentially broad application in gene regulation.

PMID:
21787382
[PubMed - indexed for MEDLINE]
PMCID:
PMC3218820
Free PMC Article

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