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Genome Biol. 2011 Jul 25;12(7):120. doi: 10.1186/gb-2011-12-7-120.

An integrated strategy for identification of both sharp and broad peaks from next-generation sequencing data.

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  • 1Department of Physics, The George Washington University, 725 21st Street NW, Washington, DC 20052, USA. wpeng@gwu.edu

Abstract

A novel integrative approach has been developed by Lieb and colleagues for analyzing genome-wide datasets of different chromatin-binding factors and epigenetic states that exhibit both sharp and diffuse signals on the genome.

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PMID:
21787381
[PubMed - indexed for MEDLINE]
PMCID:
PMC3218819
Free PMC Article
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